Restraint stress resulted in a significant reduction in tissue content of AEA within the amygdala [t (18) = 2.35, p < 0.03; Fig. 2], while there was no effect of stress on amygdalar 2-AG content [t (18) = 0.85, p > 0.05; Fig. 2]. The reduction in amygdalar AEA content following stress is likely attributable to an enhancement of hydrolysis as stress robustly increased the Vmax of FAAH for AEA hydrolysis [t (6) = 2.59, p < 0.05; Table 1]. Stress did not affect the Km of FAAH for AEA [t (6) = 1.58, p > 0.05; Table 1].
