A recent proteomic study has uncovered Bcl11b (also known as Ctip2) to be a novel, dedicated subunit of BAF which stably associates with the complex even in denaturing conditions (Kadoch et al., 2013). Bcl11b is a zing-finger domain transcription factor critical in several developmental paradigms, including T cell development (Wakabayashi et al., 2003; Albu et al., 2007, 2011; Ikawa et al., 2010) and odontogenesis (Golonzhka et al., 2009). During neural development, Bcl11b has critical roles in consolidating the subtype identities of postmitotic neurons in multiple localized regions.
