risk groups, and findings are remarkably consistent across studies. SS youth appear at greater risk for early-onset drinking, binge drinking and cannabis use, and the intervention is particularly effective in delaying such use for these higher-risk youth; large effect sizes are reported. By contrast, the AS intervention was shown to be particularly effective in promoting abstinence from alcohol and alcohol-related problems, with AS-focused trials showing that alcohol outcomes are mediated by the effect of the AS on self-medication motives for drinking [44, 64].
