The qualitative results in the presence of duplicate gene interaction (Table 8) resemble those for complementary epistasis but the symptom counts show still far greater support for G × E and the effects are largely untouched by transformation. Attempts to resolve all parameters of the full two-locus model are completely frustrated by lack of information about the critical features of the model in the dichotomous case (estimates not tabulated). In contrast to the finding in the presence of complementary epistasis, when one of the interacting loci is omitted from the models for the trait with duplicate gene interaction, estimates of the effect of the other locus are too small and far less significant than expected under the correct model.
