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Chunk #31 — Discussion — Association Analyses in the MGS control samples

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Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.
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Another significant result was the solute carrier, SLC35B4 (p=0.0015), encoding a glycosyltransferase involved in the transfer of nucleotide sugars from the cytoplasm to the Golgi apparatus for synthesis of glycoproteins (Ashikov et al. 2005). Glycosyltransferases are critical to metabolism of carbohydrates (Davies, Gloster, and Henrissat 2005) and may potentially be related to alcohol metabolism.