enriched DNA fragments (hMeDIP) or 5mC-specific MeDIP. 5hmC levels were enriched in R1,R3 and R5 in the chronic ethanol exposure. 5mC enrichment levels (associated with diminished expression) were reduced in R3 and R6. Similar effects were seen in the withdrawal condition, which suggests that reduced MeCP2 expression may be due to a combination of reduced 5hmC and increased 5mC in these regions.
