WEB-based GEne SeT AnaLysis Toolkit (WebGestalt, http://www.webgestalt.org/) was used to conduct overrepresentation analysis (ORA) of pathways, gene ontologies, phenotypes and protein-protein interactions of the top-tables and treatment-responsive modules. For each list of differentially expressed genes and treatment-responsive modules, all unique genes in the list were submitted to WebGestalt based on gene symbol. The background list for each tissue region consisted of all genes that were used to construct the network.
