For each SNP, expression quantitative trait loci (eQTLs), RBP-binding sites, and miRNA target sites were annotated. The eQTL information was retrieved from the Genotype-Tissue Expression (GTEx) database (version V7; accessed December 17, 2018) [24] to find SNPs that are eQTLs for the same gene, and also to determine whether miRNAs were expressed in brain. The UCSC Genome Browser database [25] was used to annotate whether a specific SNP was located in the binding site of an RBP using the ENCODE RNA-Binding Protein track [26]. The Polymirts database [27] was used to predict the potential miRNAs whose binding can be altered by a candidate SNP, where the binding of an miRNA on a specific target sequence was evaluated by TargetScan [28].
