Chunk #32 — Online Methods (Limit 3,000 words, at end of manuscript, currently 2,064) — Creating gene expression predictors for the dorso-lateral pre-frontal cortex — eQTL Data
The samples used here include 254 schizophrenia and 52 bipolar cases, as well as controls. The CMC flagship paper14 applied a permutation test and an explicit disease-genotype interaction term to demonstrate that there is no significant effect of disease on eQTLs. We have therefore included both cases and controls in this analysis, to maximize sample size.
