While the above analyses utilize the genome-wide data, we also conducted three analyses (Online Methods) restricted to the 16 GWAS and four proxy-phenotype SNPs in Table 1. In brief, we ascertained whether each SNP (or a variant in strong linkage disequilibrium (LD) with it) falls into any of the following three classes: (i) resides in a locus for which genome-wide significant associations with other phenotypes have been reported (Supplementary Table 22), (ii) is nonsynonymous (Supplementary Table 23), and (iii) is an eQTL in blood or in one of 14 other tissues (although the non-blood analyses are based on smaller samples) (Supplementary Table 24). Here we highlight a few particularly interesting results.
