In sum, it appears generally to be true that low levels of 5HT are associated with increased levels of emotion-based engagement in rash or ill-considered behaviors. When 5HT levels are reduced experimentally, one tends to see increases in emotion-based rash acts. It is thus quite plausible that variation in levels of 5HT for 2c and 1a receptor sites, particularly in the key areas of the PFC, facilitate the emergence of variation in the trait of urgency.
