The purpose of the current study was to extend the outcomes of our previous study on the persistency of the effects of neonatal exposure to alcohol on dendritic arborization, on spine density and on spine phenotypes in mPFC Layer II/III pyramidal neurons. Based on previous work in our lab, it was hypothesized that neonatal alcohol exposure would affect overall spine density as well as altering the density of mature and immature spines and reduce the complexity of basilar dendrites in Layer II/III pyramidal neurons.
