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Chunk #29 — DISCUSSION

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Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
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Finally, lack of an association may be influenced by variation in genotyping array coverage, because coverage affects the power to detect individual variants.65–67 Differences in coverage may explain why previous studies did not report a significant association between alcohol consumption-related traits and ALDH2 rs671 in Asian populations or ADH1B rs1229984 in European ancestry populations.