attainment phenotypes from Rietveld et al. [37]: we estimate a statistically significant negative genetic correlation between college and Alzheimer’s disease, which agrees with epidemiological results [38, 39]. The positive genetic correlation between college and bipolar disorder is consistent with previous epidemiological reports [40, 41]. The estimate of a negative genetic correlation between smoking and college is consistent with the observed differences in smoking rates as a function of educational attainment [42].
