The first section of Table 2 lists genetic correlation results that are consistent with epidemiological associations, but, as far as we are aware, have not previously been reported using genetic data. The estimates of the genetic correlation between age at menarche and adult height [29], triglycerides [30] and type 2 diabetes [30, 31] are consistent with the epidemiological associations. The estimate of a negative genetic correlation between anorexia nervosa and obesity suggests that the same genetic factors influence normal variation in BMI as well as dysregulated BMI in psychiatric illness. This result is consistent with the observation that BMI GWAS findings implicate neuronal, rather than metabolic, cell-types and epigenetic marks [32, 33]. The negative genetic correlation between adult height and coronary artery disease agrees with a replicated epidemiological association [34, 35, 36]. We observe several significant associations with the educational attainment phenotypes from Rietveld et al. [37]: we estimate a statistically significant negative genetic correlation between college and Alzheimer’s disease, which agrees with epidemiological results [38, 39]. The positive genetic correlation between college and bipolar disorder is consistent with previous
