determination of a previously identified target stimulus in an oddball paradigm. However, the smaller NOGO P3 in alcoholics compared to controls is consistent with previous studies (Ceballos et al. 2003; Cohen et al. 1997b; Ford et al. 1991; Hada et al. 2000; Kamarajan et al. 2005a; Oddy and Barry 2009; Rodriguez Holguin et al. 1999a). Indeed the identified sensitivity of P3 from the GO/NOGO to alcoholism led Kamarajan and colleagues (Kamarajan et al. 2005a) to deem the P3 elicited in the NOGO paradigm as “the electrophysiological signature of response inhibition” and an endophenotypic marker of alcoholism.
