Chunk #25 — METHODS — Example and validation

Source

SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies.

Embedded

yes

Text

Published studies have identified 43 non-overlapping linkage regions for prostate cancer. As shown in Figure 2B, we used LinkagePipe to select 266 GWAS SNPs using the following parameter values (MAF = 0.05, Maximum number of SNPs/linkage locus = 7, GWAS P threshold = 0.01, LD threshold = 0.8).