SNPinfo: integrating GWAS and candidate gene information into functional SNP selection for genetic association studies.
paper
Cited
Public
- Authors
- Xu, Zongli; Taylor, Jack A
- Year
- 2009
- Journal
- Nucleic acids research
- PMID
- 19417063
- DOI
- 10.1093/nar/gkp290
- PMCID
- PMC2703930
We have developed a set of web-based SNP selection tools (freely available at http://www.niehs.nih.gov/snpinfo) where investigators can specify genes or linkage regions and select SNPs based on GWAS results, linkage disequilibrium (LD), and predicted functional characteristics of both coding and non-coding SNPs. The algorithm uses GWAS SNP P-value data and finds all SNPs in high LD with GWAS SNPs, so that selection is from a much larger set of SNPs than the GWAS itself. The program can also identify and choose tag SNPs for SNPs not in high LD with any GWAS SNP. We incorporate functional predictions of protein structure, gene regulation, splicing and miRNA binding, and consider whether the alternative alleles of a SNP are likely to have differential effects on function. Users can assign weights for different functional categories of SNPs to further tailor SNP selection. The program accounts for LD structure of different populations so that a GWAS study from one ethnic group can be used to choose SNPs for one or more other ethnic groups. Finally, we provide an example using prostate cancer and demonstrate that this algorithm can select a small panel of SNPs that include many of the recently validated prostate cancer SNPs.
GenePipe: decision tree to prioritize SNPs for candidate genes based on GWAS results, SNP functional prediction characteristics and pair-wise LD. The six-sided boxes represent decision points and rectangles represent action steps or end points.
LLM interpretation
This figure is a decision tree flowchart illustrating the GenePipe pipeline for prioritizing SNPs for candidate genes. The process begins with a gene list and uses decision points (six-sided boxes) based on GWAS p-values and tag percentages to filter for "Selected Genes." The subsequent workflow extracts a SNP list and applies further filtersβincluding GWAS status, functional SNP prediction, and minor allele frequencyβto ultimately assign weights and select tag SNPs for reduction.
(A) GenomePipe: flow chart for functional SNP selection from SNPs that are in high LD with small P-value GWAS SNPs. (B) LinkagePipe: flow chart to prioritize SNPs in linkage loci based on P-values in GWAS.
LLM interpretation
This figure consists of two flow charts, labeled (A) and (B), illustrating bioinformatics pipelines for SNP selection. Panel A (GenomePipe) shows a process starting with GWAS SNPs, filtering by a p-value threshold (p β€ T2), extracting SNPs in high LD, identifying putative functional SNPs, and eliminating redundant SNPs. Panel B (LinkagePipe) shows a process starting with linkage loci, extracting GWAS SNPs, filtering by a p-value threshold (p β€ T3), eliminating redundant SNPs, and resulting in top-ranked SNPs by p-value.
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| Name | Type |
|---|---|
| African American | cohort |
| African-American men local | cohort |
| Asian | cohort |
| cancer | phenotype |
| Cancer Genetics Markers of Susceptibility (CGEMS) project local | cohort |
| candidate genes | cohort |
| CGEMS follow up study local | cohort |
| CGEMS GWAS local | cohort |
| CGEMS validation study local | cohort |
| chromosome region local | drug |
| common variants | cohort |
| CpG region local | drug |
| dbSNP | cohort |
| dbSNP SNP local | variant |
| disease | phenotype |
| European-American men local | cohort |
| European ancestry | cohort |
| Europeans | cohort |
| family-based samples local | cohort |
| FuncPred | drug |
| functional SNP | cohort |
| gene | gene |
| GenomePipe local | drug |
| GWAS | cohort |
| GWAS panels local | cohort |
| HapMap | cohort |
| High LD SNPs local | variant |
| Hispanic | phenotype |
| International Hapmap Project | cohort |
| JAZF1 local | gene |
| LD local | drug |
| LD tag SNP local | variant |
| LinkagePipe local | drug |
| linkage regions local | cohort |
| linkage studies | cohort |
| miRanda local | drug |
| miRBase | drug |
| miRNA | drug |
| miRNA-binding site local | drug |
| MSMB local | gene |
| MSMB SNP local | variant |
| nonsense SNP local | variant |
| non-synonymous polymorphism local | variant |
| population-based samples | cohort |
| prostate cancer | phenotype |
| rs10486567 local | variant |
| rs10896449 local | variant |
| small P-value GWAS SNP local | variant |
| small P-value SNP local | variant |
| SNP | cohort |
| SNPseq local | drug |
| splicing activity local | phenotype |
| sub-Saharan African local | cohort |
| TagSNP local | drug |
| tumor | phenotype |
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| Potential protective role of a NOD2 polymorphism in the susceptibility to multiple sclerosis is not associated with interferon therapy. | ZeΔkanoviΔ A et al. | β | 2021 | β |
| Relationship Between Interleukin-6 -174G/C Genetic Variant and Efficacy of Methotrexate Treatment in Psoriatic Arthritis Patients. | Sokolik R et al. | β | 2021 | β |
| Relevance of PD-L1 Non-Coding Polymorphisms on the Prognosis of a Genetically Admixed NSCLC Cohort. | Machado-Rugolo J et al. | β | 2021 | β |
| Shared epitope and polymorphism of <i>MICA</i> and <i>NKG2D</i> encoding genes in Greek and Polish patients with rheumatoid arthritis. | WieliΕska J et al. | β | 2021 | β |
| Significant, replicable, and functional associations between KTN1 variants and alcohol and drug codependence. | Luo X et al. | β | 2021 | β |
| SNP rs10420324 in the AMPA receptor auxiliary subunit TARP Ξ³-8 regulates the susceptibility to antisocial personality disorder. | Peng SX et al. | β | 2021 | β |
| The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression. | Azarova I et al. | β | 2021 | β |
| The role of glucocorticoid receptor gene in the association between attention deficit-hyperactivity disorder and smaller brain structures. | Bandeira CE et al. | β | 2021 | β |
| TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese population. | Li J et al. | β | 2021 | β |
| Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs. | Abdel-Motaleb AI et al. | β | 2021 | β |
| Transcription Factor-7-Like-2 (TCF7L2) in Atherosclerosis: A Potential Biomarker and Therapeutic Target. | Li J et al. | β | 2021 | β |
| Variants of <i>PCSK9</i> Gene Are Associated with Subclinical Atherosclerosis and Cardiometabolic Parameters in Mexicans. The GEA Project. | ZamarrΓ³n-Licona E et al. | β | 2021 | β |
| A Functional Synonymous Variant in <i>PDGFRA</i> Is Associated with Better Survival in Acral Melanoma. | Dai J et al. | β | 2020 | β |
| A Functional Variant of the miR-15 Family Is Associated with a Decreased Risk of Esophageal Squamous Cell Carcinoma. | Shao Y et al. | β | 2020 | β |
| Association between the <i>APOA2</i> rs3813627 Single Nucleotide Polymorphism and HDL and APOA1 Levels Through BMI. | Boughanem H et al. | β | 2020 | β |
| Association of adiponectin and adiponectin receptor gene polymorphisms with rheumatoid arthritis in a Chinese population. | Zhao YL et al. | β | 2020 | β |
| Association of BTLA rs1982809 polymorphism with lung cancer risk in Tunisian population. | Khadhraoui C et al. | β | 2020 | β |
| Association of Common Variants of <i>TNFSF13</i> and <i>TNFRSF13B</i> Genes with CLL Risk and Clinical Picture, as Well as Expression of Their Products-APRIL and TACI Molecules. | Jasek M et al. | β | 2020 | β |
| Association of Midkine and Pleiotrophin Gene Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Chinese Han Population. | Wang P et al. | β | 2020 | β |
| Associations between genetic variants of KIF5B, FMN1, and MGAT3 in the cadherin pathway and pancreatic cancer risk. | Zhao L et al. | β | 2020 | β |
| Associations of novel variants in <i>PIK3C3</i>, <i>INSR</i> and <i>MAP3K4</i> of the ATM pathway genes with pancreatic cancer risk. | Zhao LL et al. | β | 2020 | β |
| CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa). | Olvany JM et al. | β | 2020 | β |
| Clinical and Clinical-Pharmacogenetic Models for Prediction of the Most Common Psychiatric Complications Due to Dopaminergic Treatment in Parkinson's Disease. | RedenΕ‘ek S et al. | β | 2020 | β |
| Clinical relevance of the lnc-HNF1B-3:1 genetic polymorphisms in Western Chinese tuberculosis patients. | Wu Q et al. | β | 2020 | β |
| Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I.Family study and meta-analysis. | Nagrani R et al. | β | 2020 | β |
| Genetic Association Analysis of Cell Cycle Regulators Reveals <i>YWHAZ</i> Has Prognostic Significance in Prostate Cancer. | Yu CC et al. | β | 2020 | β |
| Genetic Fine Mapping and Genomic Annotation Defines Causal Mechanisms at A Novel Colorectal Cancer Susceptibility Locus in Han Chinese. | Jiang K et al. | β | 2020 | β |
| Genetic variants in m6A modification genes are associated with colorectal cancer risk. | Meng Y et al. | β | 2020 | β |
| Genetic variants of <i>BIRC3</i> and <i>NRG1</i> in the NLRP3 inflammasome pathway are associated with non-small cell lung cancer survival. | Tang D et al. | β | 2020 | β |
| Genome-wide association study identifies TPH2 variant as a novel locus for severe CV-A6-associated hand, foot, and mouth disease in Han Chinese. | Meng Y et al. | β | 2020 | β |
| Identification of Regulatory SNPs Associated with Vicine and Convicine Content of <i>Vicia faba</i> Based on Genotyping by Sequencing Data Using Deep Learning. | Heinrich F et al. | β | 2020 | β |
| IKBKB rs2272736 is Associated with Gastric Cancer Survival. | Gong Y et al. | β | 2020 | β |
| <i>KTN1</i> Variants Underlying Putamen Gray Matter Volumes and Parkinson's Disease. | Mao Q et al. | β | 2020 | β |
| Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk. | Wagner M et al. | β | 2020 | β |
| Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. | Ainsworth HC et al. | β | 2020 | β |
| <i>SFTPC</i> genetic polymorphisms are associated with tuberculosis susceptibility and clinical phenotype in a Western Chinese Han population. | Zhao JW et al. | β | 2020 | β |
| KTN1 variants and risk for attention deficit hyperactivity disorder. | Luo X et al. | β | 2020 | β |
| <i>APOB</i> Genotypes and <i>CDH13</i> Haplotypes in the Cholesterol-Related Pathway Genes Predict Non-Small Cell Lung Cancer Survival. | Deng W et al. | β | 2020 | β |
| Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer. | Tang D et al. | β | 2020 | β |
| Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival. | Yang S et al. | β | 2020 | β |
| Novel Genetic Variants of <i>ALG6</i> and <i>GALNTL4</i> of the Glycosylation Pathway Predict Cutaneous Melanoma-Specific Survival. | Zhou B et al. | β | 2020 | β |
| Novel genetic variants of <i>KIR3DL2</i> and <i>PVR</i> involved in immunoregulatory interactions are associated with non-small cell lung cancer survival. | Wu Y et al. | β | 2020 | β |
| Novel Variants of <i>ELP2</i> and <i>PIAS1</i> in the Interferon Gamma Signaling Pathway Are Associated with Non-Small Cell Lung Cancer Survival. | Zhao YC et al. | β | 2020 | β |
| Phenylethanolamine <i>N</i>-methyltransferase gene polymorphisms associate with crisis pain in sickle cell disease patients. | Sadhu N et al. | β | 2020 | β |
| Polymorphisms of genes encoding cytokines predict the risk of high-grade bladder cancer and outcomes of BCG immunotherapy. | Krajewski W et al. | β | 2020 | β |
| Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients. | Volz NB et al. | β | 2020 | β |
| Polymorphisms within the RANK and RANKL Encoding Genes in Patients with Rheumatoid Arthritis: Association with Disease Progression and Effectiveness of the Biological Treatment. | WieliΕska J et al. | β | 2020 | β |
| Potentially functional genetic variants in PLIN2, SULT2A1 and UGT1A9 genes of the ketone pathway and survival of nonsmall cell lung cancer. | Tang D et al. | β | 2020 | β |
| Prediction of genome-wide effects of single nucleotide variants on transcription factor binding. | Carrasco Pro S et al. | β | 2020 | β |
| The associations of hub gene polymorphisms in PI3K/AKT/mTOR pathway and Schistosomiasis Japonica infection and hepatic fibrosis. | Xiao Q et al. | β | 2020 | β |
| The c.*52 <i>A/G</i> and c.*773 <i>A/G</i> Genetic Variants in the UTR'3 of the <i>LDLR</i> Gene Are Associated with the Risk of Acute Coronary Syndrome and Lower Plasma HDL-Cholesterol Concentration. | Vargas-Alarcon G et al. | β | 2020 | β |
| The Current Status of Genes and Genetic Testing in Emergency Medicine: A Narrative Review. | Aghamir SMK et al. | β | 2020 | β |
| The effect of interleukin 10 polymorphisms on breast cancer susceptibility in Han women in Shaanxi Province. | Li M et al. | β | 2020 | β |
| The IL-6 rs1800795 and rs1800796 polymorphisms are associated with coronary artery disease risk. | Lu S et al. | β | 2020 | β |
| The Polymorphisms of lncRNA HOXA11-AS and the risk of Lung Cancer in Northeastern Chinese population. | Gao M et al. | β | 2020 | β |
| The Ser290Asn and Thr715Pro Polymorphisms of the <i>SELP</i> Gene Are Associated with A Lower Risk of Developing Acute Coronary Syndrome and Low Soluble P-Selectin Levels in A Mexican Population <sup>β‘</sup>. | Herrera-Maya G et al. | β | 2020 | β |
| Tropomyosin 1 genetically constrains in vitro hematopoiesis. | Thom CS et al. | β | 2020 | β |
| Turning genome-wide association study findings into opportunities for drug repositioning. | Lau A et al. | β | 2020 | β |
| Views on GWAS statistical analysis. | Cao X et al. | β | 2020 | β |
| A Common Tag Nucleotide Variant in <i>MMP7</i> Promoter Increases Risk for Hypertension via Enhanced Interactions With CREB (Cyclic AMP Response Element-Binding Protein) Transcription Factor. | Subramanian L et al. | β | 2019 | β |
| A comprehensive study revealed SNP-SNP interactions and a sex-dependent relationship between polymorphisms of the CYP2J2 gene and hypertension risk. | Polonikov AV et al. | β | 2019 | β |
| ADAR1 function affects HPV replication and is associated to recurrent human papillomavirus-induced dysplasia in HIV coinfected individuals. | Pujantell M et al. | β | 2019 | β |
| A functional variant in SLC1A3 influences ADHD risk by disrupting a hsa-miR-3171 binding site: A two-stage association study. | Huang X et al. | β | 2019 | β |
| Analysis of the Functional Relevance of Epigenetic Chromatin Marks in the First Intron Associated with Specific Gene Expression Patterns. | Jo SS et al. | β | 2019 | β |
| A phenomics-based approach for the detection and interpretation of shared genetic influences on 29 biochemical indices in southern Chinese men. | Hu Y et al. | β | 2019 | β |
| Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy. | Shi D et al. | β | 2019 | β |
| Association of Melatonin Pathway Gene's Single-Nucleotide Polymorphisms with Systemic Lupus Erythematosus in a Chinese Population. | Wang P et al. | β | 2019 | β |
| Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development. | Mesic A et al. | β | 2019 | β |
| Clinical-Pharmacogenetic Predictive Models for Time to Occurrence of Levodopa Related Motor Complications in Parkinson's Disease. | RedenΕ‘ek S et al. | β | 2019 | β |
| Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke. | Hsieh FI et al. | β | 2019 | β |
| Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function. | Ortega FJ et al. | β | 2019 | β |
| Dopaminergic Pathway Genes Influence Adverse Events Related to Dopaminergic Treatment in Parkinson's Disease. | RedenΕ‘ek S et al. | β | 2019 | β |
| Effect of genetic variants in cell adhesion pathways on the biochemical recurrence in prostate cancer patients with radical prostatectomy. | Yu CC et al. | β | 2019 | β |
| Enrichment of rare alleles within epigenetic chromatin marks in the first intron. | Jo SS et al. | β | 2019 | β |
| Exploratory Study of Associations Between DNA Repair and Oxidative Stress Gene Polymorphisms and Cognitive Problems Reported by Postmenopausal Women With and Without Breast Cancer. | Merriman JD et al. | β | 2019 | β |
| Functional variants of lncRNA LINC00673 and gastric cancer susceptibility: a case-control study in a Chinese population. | Zhao K et al. | β | 2019 | β |
| Genetic Association Between NGFR, ADAM17 Gene Polymorphism, and Parkinson's Disease in the Chinese Han Population. | Li WW et al. | β | 2019 | β |
| Genetic Screening of Plasticity Regulating Nogo-Type Signaling Genes in Migraine. | Smedfors G et al. | β | 2019 | β |
| Genetic variability of inflammation and oxidative stress genes does not play a major role in the occurrence of adverse events of dopaminergic treatment in Parkinson's disease. | RedenΕ‘ek S et al. | β | 2019 | β |
| Genetic variants of cGMP-dependent protein kinase genes and salt sensitivity of blood pressure: the GenSalt study. | Han C et al. | β | 2019 | β |
| Genomic variants in members of the KrΓΌppel-like factor gene family are associated with disease severity and hydroxyurea treatment efficacy in Ξ²-hemoglobinopathies patients. | Stratopoulos A et al. | β | 2019 | β |
| <i>C1QA</i> and <i>C1QC</i> modify age-at-onset in familial amyloid polyneuropathy patients. | Dias A et al. | β | 2019 | β |
| Impact of autism-associated genetic variants in interaction with environmental factors on ADHD comorbidities: an exploratory pilot study. | Waltes R et al. | β | 2019 | β |
| Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease. | Polonikov A et al. | β | 2019 | β |
| miR-196a2 (rs11614913) polymorphism is associated with coronary artery disease, but not with in-stent coronary restenosis. | Fragoso JM et al. | β | 2019 | β |
| Phenotype Prediction and Genome-Wide Association Study Using Deep Convolutional Neural Network of Soybean. | Liu Y et al. | β | 2019 | β |
| Pneumonia: host susceptibility and shared genetics with pulmonary function and other traits. | Khadzhieva MB et al. | β | 2019 | β |
| Polymorphism in CYP24A1 Is Associated with Lung Cancer Risk: A Case-Control Study in Chinese Female Nonsmokers. | Qu R et al. | β | 2019 | β |
| Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs. | Perkins JR et al. | β | 2019 | β |
| Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer. | Feng Y et al. | β | 2019 | β |
| Potentially functional genetic variants in the TNF/TNFR signaling pathway genes predict survival of patients with non-small cell lung cancer in the PLCO cancer screening trial. | Guo Y et al. | β | 2019 | β |
| Prognostic Value of <i>CD1B</i> in Localised Prostate Cancer. | Lee CH et al. | β | 2019 | β |
| SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population. | Vargas-Alarcon G et al. | β | 2019 | β |
| The -44 C/G (rs1800972) polymorphism of the Ξ²-defensin 1 is associated with increased risk of developing type 2 diabetes mellitus. | Martinez-Rios MA et al. | β | 2019 | β |
| Three novel genetic variants in NRF2 signaling pathway genes are associated with pancreatic cancer risk. | Yang W et al. | β | 2019 | β |
| TNF-Ξ± promoter polymorphisms (G-238A and G-308A) are associated with susceptibility to Systemic Lupus Erythematosus (SLE) and P. falciparum malaria: a study in malaria endemic area. | Mahto H et al. | β | 2019 | β |
| Variants in the PSCA gene associated with risk of cancer and nonneoplastic diseases: systematic research synopsis, meta-analysis and epidemiological evidence. | Cui H et al. | β | 2019 | β |
| Variations in circadian genes and individual nocturnal symptoms of insomnia. The HUNT study. | Bragantini D et al. | β | 2019 | β |
| VIPdb, a genetic Variant Impact Predictor Database. | Hu Z et al. | β | 2019 | β |
| A Comprehensive <i>in Silico</i> Analysis of Regulatory SNPs of Human CLEC7A Gene and Its Validation as Genotypic and Phenotypic Disease Marker in Recurrent Vulvovaginal Infections. | Kalia N et al. | β | 2018 | β |
| A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety. | Hommers LG et al. | β | 2018 | β |
| A Functional riboSNitch in the 3' Untranslated Region of <i>FKBP5</i> Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain. | Linnstaedt SD et al. | β | 2018 | β |
| A Novel Polymorphism in the Promoter of the <i>CYP4A11</i> Gene Is Associated with Susceptibility to Coronary Artery Disease. | Sirotina S et al. | β | 2018 | β |
| Association Between Long Noncoding RNA MEG3 Polymorphisms and Lung Cancer Susceptibility in Chinese Northeast Population. | Yang Z et al. | β | 2018 | β |
| Association of Optic Neuritis with <i>CYP4F2</i> Gene Single Nucleotide Polymorphism and IL-17A Concentration. | Banevicius M et al. | β | 2018 | β |
| Association of TUSC1 and DPF3 gene polymorphisms with male infertility. | Sato Y et al. | β | 2018 | β |
| Associations of NADPH oxidase-related genes with blood pressure changes and incident hypertension: The GenSalt Study. | Li H et al. | β | 2018 | β |
| Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing. | Madhukar NS et al. | β | 2018 | β |
| Clinical Pharmacogenetic Models of Treatment Response to Methotrexate Monotherapy in Slovenian and Serbian Rheumatoid Arthritis Patients: Differences in Patient's Management May Preclude Generalization of the Models. | Jenko B et al. | β | 2018 | β |
| Clinical significance of glutamate metabotropic receptors in renal cell carcinoma risk and survival. | Huang CY et al. | β | 2018 | β |
| Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities. | Chiocchetti AG et al. | β | 2018 | β |
| Cytokine Gene Polymorphisms Associated With Various Domains of Quality of Life in Women With Breast Cancer. | Alexander K et al. | β | 2018 | β |
| Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. | Xu Y et al. | β | 2018 | β |
| Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. | Li B et al. | β | 2018 | β |
| Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk. | Duan B et al. | β | 2018 | β |
| Genetic variation of the gene coding for microRNA-204 (miR-204) is a risk factor in acute myeloid leukaemia. | Butrym A et al. | β | 2018 | β |
| Genome-wide scan identifies candidate loci related to remifentanil requirements during laparoscopic-assisted colectomy. | Nishizawa D et al. | β | 2018 | β |
| GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population. | Yin JY et al. | β | 2018 | β |
| <i>BSG</i> and <i>MCT1</i> Genetic Variants Influence Survival in Multiple Myeloma Patients. | Εacina P et al. | β | 2018 | β |
| Identification of a functional FADS1 3'UTR variant associated with erythrocyte n-6 polyunsaturated fatty acids levels. | Hermant X et al. | β | 2018 | β |
| Importance of common TLR2 genetic variants on clinical phenotypes and risk in tuberculosis disease in a Western Chinese population. | Zhang J et al. | β | 2018 | β |
| Importance of genetic background of oxysterol signaling in cancer. | Holy P et al. | β | 2018 | β |
| Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis. | Iwaszko M et al. | β | 2018 | β |
| Integrative genomic analysis of methylphenidate response in attention-deficit/hyperactivity disorder. | Pagerols M et al. | β | 2018 | β |
| K<sub>ATP</sub> Channel Expression and Genetic Polymorphisms Associated with Progression and Survival in Amyotrophic Lateral Sclerosis. | Vidal-Taboada JM et al. | β | 2018 | β |
| Modification of the association between antipsychotic treatment response and childhood adversity by MMP9 gene variants in a first-episode schizophrenia cohort. | McGregor N et al. | β | 2018 | β |
| NF-kB2 Genetic Variations are Significantly Associated with Non-Small Cell Lung Cancer Risk and Overall Survival. | Dimitrakopoulos FD et al. | β | 2018 | β |
| No association between G1359A CB1 polymorphisms and pain in young northeastern Mexicans. | RodrΓguez-RodrΓguez IA et al. | β | 2018 | β |
| Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer. | Feng Y et al. | β | 2018 | β |
| Polymorphism of the DNA methyltransferase 1 gene is associated with the susceptibility to essential hypertension in male. | Chen HL et al. | β | 2018 | β |
| Positive Association between <i>EDN1</i> rs5370 (Lys198Asn) Polymorphism and Large Artery Stroke in a Ukrainian Population. | Dubovyk YI et al. | β | 2018 | β |
| Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. | Freedman JA et al. | β | 2018 | β |
| 19p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese. | Hou W et al. | β | 2017 | β |
| A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels. | Lee JD et al. | β | 2017 | β |
| A comprehensive contribution of genes for aryl hydrocarbon receptor signaling pathway to hypertension susceptibility. | Polonikov AV et al. | β | 2017 | β |
| A functional polymorphism of <i>SSBP1</i> gene predicts prognosis and response to chemotherapy in resected gastric cancer patients. | Li Q et al. | β | 2017 | β |
| A functional SNP regulated by miR-196a-3p in the 3'UTR of FGF2 is associated with bone mineral density in the Chinese population. | Zhu DL et al. | β | 2017 | β |
| A functional SNP rs1892901 in FOSL1 is associated with gastric cancer in Chinese population. | Liu W et al. | β | 2017 | β |
| A potentially functional polymorphism in ABCG2 predicts clinical outcome of non-small cell lung cancer in a Chinese population. | Sun J et al. | β | 2017 | β |
| Association between single nucleotide polymorphisms in the antioxidant genes <i>CAT</i>, <i>GR</i> and <i>SOD1</i>, erythrocyte enzyme activities, dietary and life style factors and breast cancer risk in a Danish, prospective cohort study. | Kopp TI et al. | β | 2017 | β |
| Association of a 3' untranslated region polymorphism in proprotein convertase subtilisin/kexin type 9 with HIV viral load and CD4+ levels in HIV/hepatitis C virus coinfected women. | Kuniholm MH et al. | β | 2017 | β |
| Association of leptin and leptin receptor gene polymorphisms with systemic lupus erythematosus in a Chinese population. | Li HM et al. | β | 2017 | β |
| Association of TNFSF13 polymorphisms with IgA nephropathy in a Chinese Han population. | Zhong Z et al. | β | 2017 | β |
| Associations between genetic variants in immunoregulatory genes and risk of non-Hodgkin lymphoma in a Chinese population. | Ye X et al. | β | 2017 | β |
| Associations Between Genetic Variants of NADPH Oxidase-Related Genes and Blood Pressure Responses to Dietary Sodium Intervention: The GenSalt Study. | Han X et al. | β | 2017 | β |
| Associations of PARP-1 variant rs1136410 with PARP activities, oxidative DNA damage, and the risk of age-related cataract in a Chinese Han population: A two-stage case-control analysis. | Cui NH et al. | β | 2017 | β |
| A Survey of Software and Hardware Approaches to Performing Read Alignment in Next Generation Sequencing. | Al Kawam A et al. | β | 2017 | β |
| Candidate novel long noncoding RNAs, MicroRNAs and putative drugs for Parkinson's disease using a robust and efficient genome-wide association study. | Mortezaei Z et al. | β | 2017 | β |
| CELSR2 is a candidate susceptibility gene in idiopathic scoliosis. | Einarsdottir E et al. | β | 2017 | β |
| Clinical-pharmacogenetic predictive models for MTX discontinuation due to adverse events in rheumatoid arthritis. | Jenko B et al. | β | 2017 | β |
| Common <i>TDP1</i> Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium. | Lohavanichbutr P et al. | β | 2017 | β |
| Cytokine Gene Polymorphisms Associated With Symptom Clusters in Oncology Patients Undergoing Radiation Therapy. | Miaskowski C et al. | β | 2017 | β |
| Evaluation of genetic variants in autophagy pathway genes as prognostic biomarkers for breast cancer. | Zhou J et al. | β | 2017 | β |
| Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression. | Chen Y et al. | β | 2017 | β |
| Genetic Effects on the Correlation Structure ofΒ CVD Risk Factors: Exome-Wide Data From a Ghanaian Population. | Kodaman N et al. | β | 2017 | β |
| Genetic variants associated with colorectal brain metastases susceptibility and survival. | Stremitzer S et al. | β | 2017 | β |
| Genetic variants in the 3' untranslated region of sFRP1 gene and risk of gastric cancer in a Chinese population. | Wu J et al. | β | 2017 | β |
| Genetic variants in the integrin signaling pathway genes predict cutaneous melanoma survival. | Li H et al. | β | 2017 | β |
| Genetic variants of cell cycle pathway genes predict disease-free survival of hepatocellular carcinoma. | Liu S et al. | β | 2017 | β |
| Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium. | Feng Y et al. | β | 2017 | β |
| Genetic variation at the microRNA binding site of CAV1 gene is associated with lung cancer susceptibility. | Fang X et al. | β | 2017 | β |
| Genetic variation in the gene <i>LRP2</i> increases relapse risk in multiple sclerosis. | Zhou Y et al. | β | 2017 | β |
| Gene-wide Association Study Reveals RNF122 Ubiquitin Ligase as a Novel Susceptibility Gene for Attention Deficit Hyperactivity Disorder. | Garcia-MartΓnez I et al. | β | 2017 | β |
| Genome-wide integrative analysis identified SNP-miRNA-mRNA interaction networks in peripheral blood mononuclear cells. | Lin X et al. | β | 2017 | β |
| Host genetics and dengue fever. | Xavier-Carvalho C et al. | β | 2017 | β |
| Inherited Variation in Cytokine, Acute Phase Response, and Calcium Metabolism Genes Affects Susceptibility to Infective Endocarditis. | Ponasenko AV et al. | β | 2017 | β |
| Integrative multi-omics analysis revealed SNP-lncRNA-mRNA (SLM) networks in human peripheral blood mononuclear cells. | Xia W et al. | β | 2017 | β |
| Leptin Receptor Gene Variant rs11804091 Is Associated with BMI and Insulin Resistance in Spanish Female Obese Children: A Case-Control Study. | Olza J et al. | β | 2017 | β |
| Matrix Metalloproteinases Polymorphisms as Prognostic Biomarkers in Malignant Pleural Mesothelioma. | Ε trbac D et al. | β | 2017 | β |
| Multiple functional SNPs in differentially expressed genes modify risk and survival of non-small cell lung cancer in Chinese female non-smokers. | Fang X et al. | β | 2017 | β |
| Novel HLA-DP region susceptibility loci associated with severe acute GvHD. | Goyal RK et al. | β | 2017 | β |
| Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. | Yin J et al. | β | 2017 | β |
| PD-1 gene polymorphic variation is linked with first symptom of disease and severity of relapsing-remitting form of MS. | Pawlak-Adamska E et al. | β | 2017 | β |
| Pharmacogenetic Analysis of Functional Glutamate System Gene Variants and Clinical Response to Clozapine. | Taylor DL et al. | β | 2017 | β |
| Polymorphisms in CARS are associated with gastric cancer risk: a two-stage case-control study in the Chinese population. | Tian T et al. | β | 2017 | β |
| Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival. | Yang YP et al. | β | 2017 | β |
| Polymorphisms of CYP2C8, CYP2C9 and CYP2C19 and risk of coronary heart disease in Russian population. | Polonikov A et al. | β | 2017 | β |
| Population Pharmacokinetic Modeling of Tenofovir in the Genital Tract of Male HIV-Infected Patients. | Valade E et al. | β | 2017 | β |
| Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy. | Le Z et al. | β | 2017 | β |
| Preliminary Study on the Role of TMEM39A Gene in Multiple Sclerosis. | Wagner M et al. | β | 2017 | β |
| Response from Original Authors - RE: Six novel rare nonsynonymous mutations for migraine without aura identified by exome sequencing. | Wang XP et al. | β | 2017 | β |
| Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility. | Mesic A et al. | β | 2017 | β |
| Single nucleotide variants in metastasis-related genes are associated with breast cancer risk, by lymph node involvement and estrogen receptor status, in women with European and African ancestry. | Roberts MR et al. | β | 2017 | β |
| SLC6A1 gene involvement in susceptibility to attention-deficit/hyperactivity disorder: A case-control study and gene-environment interaction. | Yuan FF et al. | β | 2017 | β |
| Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs. | Zhou F et al. | β | 2017 | β |
| The Association of SNAP25 Gene Polymorphisms in Attention Deficit/Hyperactivity Disorder: a Systematic Review and Meta-Analysis. | Liu YS et al. | β | 2017 | β |
| The NLRP3 and CASP1 gene polymorphisms are associated with developing of acute coronary syndrome: a case-control study. | Gonzalez-Pacheco H et al. | β | 2017 | β |
| The T>A (rs11646213) gene polymorphism of cadherin-13 (CDH13) gene is associated with decreased risk of developing hypertension in Mexican population. | Vargas-Alarcon G et al. | β | 2017 | β |
| TNF receptors 1 and 2 exert distinct region-specific effects on striatal and hippocampal grey matter volumes (VBM) in healthy adults. | Stacey D et al. | β | 2017 | β |
| Two <i>CHRN</i> susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients. | Zhao Z et al. | β | 2017 | β |
| Variation within <i>MBP</i> gene predicts disease course in multiple sclerosis. | Zhou Y et al. | β | 2017 | β |
| Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in Ξ²-type hemoglobinopathy patients. | Chondrou V et al. | β | 2017 | β |
| A candidate gene investigation of methylphenidate response in adult attention-deficit/hyperactivity disorder patients: results from a naturalistic study. | Hegvik TA et al. | β | 2016 | β |
| A comprehensive in silico analysis of non-synonymous and regulatory SNPs of human MBL2 gene. | Kalia N et al. | β | 2016 | β |
| Adaptive evolution of interleukin-3 (IL3), a gene associated with brain volume variation in general human populations. | Li M et al. | β | 2016 | β |
| Adenosine Hypothesis of Antipsychotic Drugs Revisited: Pharmacogenomics Variation in Nonacute Schizophrenia. | TurΔin A et al. | β | 2016 | β |
| A Genomics-Based Model for Prediction of Severe Bioprosthetic Mitral Valve Calcification. | Ponasenko AV et al. | β | 2016 | β |
| Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients. | Gnanasambandan R et al. | β | 2016 | β |
| Association of 3' nearby gene BTLA polymorphisms with the risk of renal cell carcinoma in the Polish population. | Partyka A et al. | β | 2016 | β |
| Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever. | Dang TN et al. | β | 2016 | β |
| Association of DARS gene polymorphisms with the risk of isolated ventricular septal defects in the Chinese Han population. | Feng Y et al. | β | 2016 | β |
| Association of MMP-2 gene haplotypes with thoracic aortic dissection in chinese han population. | Liu O et al. | β | 2016 | β |
| Association of TLR and TREM-1 gene polymorphisms with atherosclerosis severity in a Russian population. | Kutikhin AG et al. | β | 2016 | β |
| Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia. | Jasek M et al. | β | 2016 | β |
| Associations Between Fetal Imprinted Genes and Maternal Blood Pressure in Pregnancy. | Petry CJ et al. | β | 2016 | β |
| Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence. | Zuo L et al. | β | 2016 | β |
| Association study involving polymorphisms in IL-6, IL-1RA, and CTLA4 genes and rheumatic heart disease in New Zealand population of MΔori and Pacific ancestry. | Azevedo PM et al. | β | 2016 | β |
| Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain. | Zai CC et al. | β | 2016 | β |
| A variant at a potentially functional microRNA-binding site in BRIP1 was associated with risk of squamous cell carcinoma of the head and neck. | Liu H et al. | β | 2016 | β |
| Biological findings from the PheWAS catalog: focus on connective tissue-related disorders (pelvic floor dysfunction, abdominal hernia, varicose veins and hemorrhoids). | Salnikova LE et al. | β | 2016 | β |
| Correlation of SIN3A genomic variants with Ξ²-hemoglobinopathies disease severity and hydroxyurea treatment efficacy. | Gravia A et al. | β | 2016 | β |
| Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. | Fehringer G et al. | β | 2016 | β |
| Endothelin 1 gene is not a major modifier of chronic kidney disease advancement among the autosomal dominant polycystic kidney disease patients. | Annapareddy SN et al. | β | 2016 | β |
| ErbB4 Gene Polymorphism Is Associated With the Risk and Prognosis of Congestive Heart Failure in a Northern Han Chinese Population. | Wang Y et al. | β | 2016 | β |
| Evaluating the Role of Genetic Variants on first-line antiepileptic drug response in North India: Significance of SCN1A and GABRA1 Gene Variants in Phenytoin Monotherapy and its Serum Drug Levels. | Baghel R et al. | β | 2016 | β |
| Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese. | Yin J et al. | β | 2016 | β |
| Genetic association analysis of N-methyl-D-aspartate receptor subunit gene GRIN2B and clinical response to clozapine. | Taylor DL et al. | β | 2016 | β |
| Genetic dissection of host immune response in pneumonia development and progression. | Smelaya TV et al. | β | 2016 | β |
| Genetic polymorphisms associated with overweight and obesity in uncontrolled Type 2 diabetes mellitus. | Kasim NB et al. | β | 2016 | β |
| Genetic polymorphisms in circadian negative feedback regulation genes predict overall survival and response to chemotherapy in gastric cancer patients. | Qu F et al. | β | 2016 | β |
| Genetic polymorphisms of mTOR and cancer risk: a systematic review and updated meta-analysis. | Zining J et al. | β | 2016 | β |
| Genetic variant in DNA repair gene GTF2H4 is associated with lung cancer risk: a large-scale analysis of six published GWAS datasets in the TRICL consortium. | Wang M et al. | β | 2016 | β |
| Genetic variants in ABCG1 are associated with survival of nonsmall-cell lung cancer patients. | Wang Y et al. | β | 2016 | β |
| Genetic variants in the mTOR pathway and interaction with body size and weight gain on breast cancer risk in African-American and European American women. | Cheng TY et al. | β | 2016 | β |
| Genetic variants in the PIWI-piRNA pathway gene DCP1A predict melanoma disease-specific survival. | Zhang W et al. | β | 2016 | β |
| Genetic variants of genes in the Notch signaling pathway predict overall survival of non-small cell lung cancer patients in the PLCO study. | Xu Y et al. | β | 2016 | β |
| Genetic variants within microRNA-binding site of RAD51B are associated with risk of cervical cancer in Chinese women. | Hang D et al. | β | 2016 | β |
| Genome-wide association study identifies candidate loci associated with postoperative fentanyl requirements after laparoscopic-assisted colectomy. | Mieda T et al. | β | 2016 | β |
| Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets. | Chen J et al. | β | 2016 | β |
| Identification of Susceptibility Genes of Adult Asthma in French Canadian Women. | BΓ©rubΓ© JC et al. | β | 2016 | β |
| Influence of CD94 and NKG2A variants on susceptibility to rheumatoid arthritis and efficacy of anti-TNF treatment. | Iwaszko M et al. | β | 2016 | β |
| In Silico Analysis of SNPs in <i>PARK2</i> and <i>PINK1</i> Genes That Potentially Cause Autosomal Recessive Parkinson Disease. | Bakhit YH et al. | β | 2016 | β |
| Interaction between polyunsaturated fatty acids and genetic variants in relation to breast cancer incidence. | Khankari NK et al. | β | 2016 | β |
| Intragenic Variations in BTLA Gene Influence mRNA Expression of BTLA Gene in Chronic Lymphocytic Leukemia Patients and Confer Susceptibility to Chronic Lymphocytic Leukemia. | Karabon L et al. | β | 2016 | β |
| NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis. | Zhao X et al. | β | 2016 | β |
| NOS1 and SNAP25 polymorphisms are associated with Attention-Deficit/Hyperactivity Disorder symptoms in adults but not in children. | Salatino-Oliveira A et al. | β | 2016 | β |
| Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study. | White MJ et al. | β | 2016 | β |
| Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls. | Kang X et al. | β | 2016 | β |
| Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy. | Jia Z et al. | β | 2016 | β |
| Prognostic Significance of Tag SNP rs1045411 in HMGB1 of the Aggressive Gastric Cancer in a Chinese Population. | Bao G et al. | β | 2016 | β |
| Prognostic Value of Prostaglandin-endoperoxide Synthase 2 Polymorphisms in Prostate Cancer Recurrence after Radical Prostatectomy. | Lee CH et al. | β | 2016 | β |
| Providing data science support for systems pharmacology and its implications to drug discovery. | Hart T et al. | β | 2016 | β |
| Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence. | Zuo L et al. | β | 2016 | β |
| STAT3 polymorphisms may predict an unfavorable response to first-line platinum-based therapy for women with advanced serous epithelial ovarian cancer. | Permuth-Wey J et al. | β | 2016 | β |
| Variants in RBP4 and AR genes modulate age at onset in familial amyloid polyneuropathy (FAP ATTRV30M). | Santos D et al. | β | 2016 | β |
| A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD). | Grassmann F et al. | β | 2015 | β |
| Addressing population-specific multiple testing burdens in genetic association studies. | Sobota RS et al. | β | 2015 | β |
| A genome-wide association study of body mass index across early life and childhood. | Warrington NM et al. | β | 2015 | β |
| A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer. | Stegeman S et al. | β | 2015 | β |
| A potentially functional variant in the serotonin transporter gene is associated with premenopausal and perimenopausal hot flashes. | Montasser ME et al. | β | 2015 | β |
| Association between WT1 polymorphisms and susceptibility to breast cancer: results from a case-control study in a southwestern Chinese population. | Qi XW et al. | β | 2015 | β |
| Associations of common variants in the BST2 region with HIV-1 acquisition in African American and European American people who inject drugs. | Hancock DB et al. | β | 2015 | β |
| Associations of Polymorphisms in MTHFR Gene with the Risk of Age-Related Cataract in Chinese Han Population: A Genotype-Phenotype Analysis. | Wang XB et al. | β | 2015 | β |
| BAYESIAN GROUP LASSO FOR NONPARAMETRIC VARYING-COEFFICIENT MODELS WITH APPLICATION TO FUNCTIONAL GENOME-WIDE ASSOCIATION STUDIES. | Li J et al. | β | 2015 | β |
| Case-control genome-wide association study of persistent attention-deficit hyperactivity disorder identifies FBXO33 as a novel susceptibility gene for the disorder. | SΓ‘nchez-Mora C et al. | β | 2015 | β |
| Childhood asthma is associated with polymorphic markers of PROC on 2q14 in addition to 17q21 locus. | Chan WC et al. | β | 2015 | β |
| Combined Whole Methylome and Genomewide Association Study Implicates CNTN4 in Alcohol Use. | Clark SL et al. | β | 2015 | β |
| Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk. | Chornokur G et al. | β | 2015 | β |
| Converging evidence implicates the abnormal microRNA system in schizophrenia. | Zhang F et al. | β | 2015 | β |
| Effects of interaction between genetic variants in human leukocyte antigen DQ and granulysin genes in Chinese Han subjects infected with hepatitis B virus. | Hou SH et al. | β | 2015 | β |
| Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer. | Lavender N et al. | β | 2015 | β |
| Expression quantitative trait loci (eQTLs) in microRNA genes are enriched for schizophrenia and bipolar disorder association signals. | Williamson VS et al. | β | 2015 | β |
| Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility. | Baskin R et al. | β | 2015 | β |
| Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer. | Volz NB et al. | β | 2015 | β |
| Genetic differences among ethnic groups. | Huang T et al. | β | 2015 | β |
| Genetic effect of transforming growth factor alpha gene variants on the risk of nonsyndromic cleft lip with or without palate in korean populations. | Kim BM et al. | β | 2015 | β |
| Genetic polymorphisms in DNA repair and oxidative stress pathways may modify the association between body size and postmenopausal breast cancer. | McCullough LE et al. | β | 2015 | β |
| Genetic Polymorphisms in the Dopamine Receptor 2 Predict Acute Pain Severity After Motor Vehicle Collision. | Qadri YJ et al. | β | 2015 | β |
| Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population. | White MJ et al. | β | 2015 | β |
| Genetic study of complex diseases in the post-GWAS era. | Huang Q | β | 2015 | β |
| Genetic variants in arachidonic acid pathway genes associated with NSAID-exacerbated respiratory disease. | Ayuso P et al. | β | 2015 | β |
| Genetic variants in fanconi anemia pathway genes BRCA2 and FANCA predict melanoma survival. | Yin J et al. | β | 2015 | β |
| Genetic variants in genes of tricarboxylic acid cycle key enzymes are associated with prognosis of patients with non-small cell lung cancer. | Guo X et al. | β | 2015 | β |
| Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population. | Sun P et al. | β | 2015 | β |
| Genetic variations in angiopoietin and pericyte pathways and clinical outcome in patients with resected colorectal liver metastases. | Stremitzer S et al. | β | 2015 | β |
| Genetic variations in monocarboxylate transporter genes as predictors of clinical outcomes in non-small cell lung cancer. | Guo X et al. | β | 2015 | β |
| Genetic variations in SLC3A2/CD98 gene as prognosis predictors in non-small cell lung cancer. | Guo X et al. | β | 2015 | β |
| Genome-wide Gene-Asbestos Exposure Interaction Association Study Identifies a Common Susceptibility Variant on 22q13.31 Associated with Lung Cancer Risk. | Liu CY et al. | β | 2015 | β |
| Glutamate Networks Implicate Cognitive Impairments in Schizophrenia: Genome-Wide Association Studies of 52 Cognitive Phenotypes. | Ohi K et al. | β | 2015 | β |
| Identification of epidermal growth factor receptor (EGFR) genetic variants that modify risk for head and neck squamous cell carcinoma. | Fung C et al. | β | 2015 | β |
| Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. | Fischer A et al. | β | 2015 | β |
| Interleukin polymorphisms associated with overall survival, disease-free survival, and recurrence in non-small cell lung cancer patients. | Woods NT et al. | β | 2015 | β |
| LPHN3 and attention-deficit/hyperactivity disorder: a susceptibility and pharmacogenetic study. | Bruxel EM et al. | β | 2015 | β |
| MicroRNA polymorphisms as markers of risk, prognosis and treatment response in hematological malignancies. | Dzikiewicz-Krawczyk A | β | 2015 | β |
| MS risk allele rs1883832T is associated with decreased mRNA expression of CD40. | Wagner M et al. | β | 2015 | β |
| NFKB1 common variants and PPP1R13L and CD3EAP in relation to lung cancer risk in a Chinese population. | Yin J et al. | β | 2015 | β |
| Optimizing multiple sclerosis diagnosis: gene expression and genomic association. | Gurevich M et al. | β | 2015 | β |
| Polymorphisms in CD28, CTLA-4, CD80 and CD86 genes may influence the risk of multiple sclerosis and its age of onset. | Wagner M et al. | β | 2015 | β |
| Polymorphisms in genes of the BAFF/APRIL system may constitute risk factors of B-CLL--a preliminary study on a Polish population. | Jasek M et al. | β | 2015 | β |
| Polymorphisms in RNA sensing toll like receptor genes and its association with clinical outcomes of dengue virus infection. | Alagarasu K et al. | β | 2015 | β |
| Polymorphisms within the human leucocyte antigen-E gene and their associations with susceptibility to rheumatoid arthritis as well as clinical outcome of anti-tumour necrosis factor therapy. | Iwaszko M et al. | β | 2015 | β |
| Potentially functional polymorphisms in aminoacyl-tRNA synthetases genes are associated with breast cancer risk in a Chinese population. | He Y et al. | β | 2015 | β |
| ReMo-SNPs: a new software tool for identification of polymorphisms in regions and motifs genome-wide. | Graae L et al. | β | 2015 | β |
| Role of SLMAP genetic variants in susceptibility of diabetes and diabetic retinopathy in Qatari population. | Upadhyay R et al. | β | 2015 | β |
| SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer. | Tian J et al. | β | 2015 | β |
| SNP rs2057482 in HIF1A gene predicts clinical outcome of aggressive hepatocellular carcinoma patients after surgery. | Guo X et al. | β | 2015 | β |
| The association of folate pathway and DNA repair polymorphisms with susceptibility to childhood acute lymphoblastic leukemia. | GoriΔar K et al. | β | 2015 | β |
| The interleukin-1Ξ²-511 T>C (rs16944) gene polymorphism is associated with risk of developing silent myocardial ischemia in diabetic patients. | Vargas-AlarcΓ³n G et al. | β | 2015 | β |
| Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women. | Mackelprang RD et al. | β | 2015 | β |
| TP53 Arg72Pro polymorphism (rs1042522) and risk of endometriosis among Asian and Caucasian populations. | Li J et al. | β | 2015 | β |
| Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth. | Christiaens I et al. | β | 2015 | β |
| Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases. | Stremitzer S et al. | β | 2015 | β |
| Variations in genes involved in immune response checkpoints and association with outcomes in patients with resected colorectal liver metastases. | Stremitzer S et al. | β | 2015 | β |
| A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. | Sanchez-Juan P et al. | β | 2014 | β |
| A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia. | GonΓ§alves VF et al. | β | 2014 | β |
| A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome. | Dang TN et al. | β | 2014 | β |
| Association of aminoacyl-tRNA synthetases gene polymorphisms with the risk of congenital heart disease in the Chinese Han population. | Da M et al. | β | 2014 | β |
| Association of gamma-aminobutyric acid A receptor Ξ±2 gene (GABRA2) with alcohol use disorder. | Li D et al. | β | 2014 | β |
| Association of genetic polymorphisms for glutathione peroxidase genes with obesity in Spanish children. | RupΓ©rez AI et al. | β | 2014 | β |
| Associations of epithelial sodium channel genes with blood pressure changes and hypertension incidence: the GenSalt study. | Yang X et al. | β | 2014 | β |
| A tool for mapping Single Nucleotide Polymorphisms using Graphics Processing Units. | Manconi A et al. | β | 2014 | β |
| Characterization of the LECT2 gene and its associations with resistance to the big belly disease in Asian seabass. | Fu GH et al. | β | 2014 | β |
| Common genetic variants in NEFL influence gene expression and neuroblastoma risk. | Capasso M et al. | β | 2014 | β |
| Common genetic variants on 1p13.2 associate with risk of autism. | Xia K et al. | β | 2014 | β |
| Cross-sectional and longitudinal replication analyses of genome-wide association loci of type 2 diabetes in Han Chinese. | Zhao Q et al. | β | 2014 | β |
| Evaluation of functional genetic variants at 6q25.1 and risk of breast cancer in a Chinese population. | Wang Y et al. | β | 2014 | β |
| Functional single nucleotide polymorphisms of the RASSF3 gene and susceptibility to squamous cell carcinoma of the head and neck. | Guo H et al. | β | 2014 | β |
| Genetic association between germline JAK2 polymorphisms and myeloproliferative neoplasms in Hong Kong Chinese population: a case-control study. | Koh SP et al. | β | 2014 | β |
| Genetic variant in SWI/SNF complexes influences hepatocellular carcinoma risk: a new clue for the contribution of chromatin remodeling in carcinogenesis. | Zhong R et al. | β | 2014 | β |
| Genetic variants in let-7/Lin28 modulate the risk of oral cavity cancer in a Chinese Han population. | Zhang Y et al. | β | 2014 | β |
| Genetic variants in SMARC genes are associated with DNA damage levels in Chinese population. | Gong J et al. | β | 2014 | β |
| Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients. | Zhang H et al. | β | 2014 | β |
| Gene variation in IL10 and susceptibility to chronic hepatitis B. | Zhang TC et al. | β | 2014 | β |
| Genome-wide association study identifies variants in PMS1 associated with serum ferritin in a Chinese population. | Liao M et al. | β | 2014 | β |
| Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA. | Earp MA et al. | β | 2014 | β |
| Genome-wide linkage and regional association study of obesity-related phenotypes: the GenSalt study. | Liu AY et al. | β | 2014 | β |
| Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study. | Deroo LA et al. | β | 2014 | β |
| Immunization associated with erectile dysfunction based on cross-sectional and genetic analyses. | Chen Y et al. | β | 2014 | β |
| Inherited variation in the PARP1 gene and survival from melanoma. | Davies JR et al. | β | 2014 | β |
| Investigation of gene-gene interactions between CD40 and CD40L in Polish multiple sclerosis patients. | Wagner M et al. | β | 2014 | β |
| Investigation of Parental Transmission of RUNX2 Single Nucleotide Polymorphism and Its Association With Nonsyndromic Cleft Lip With or Without Palate. | Jung SH et al. | β | 2014 | β |
| Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. | Zhang B et al. | β | 2014 | β |
| Male-specific genetic effect on hypertension and metabolic disorders. | Heo SG et al. | β | 2014 | β |
| Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. | Wen W et al. | β | 2014 | β |
| MicroRNA-binding site polymorphisms in hematological malignancies. | Dzikiewicz-Krawczyk A | β | 2014 | β |
| MicroRNA-binding site SNPs in deregulated genes are associated with clinical outcome of non-small cell lung cancer. | Xu J et al. | β | 2014 | β |
| MPHOSPH1: a potential therapeutic target for hepatocellular carcinoma. | Liu X et al. | β | 2014 | β |
| Peptidoglycan recognition protein genes and risk of Parkinson's disease. | Goldman SM et al. | β | 2014 | β |
| Polymorphisms in translesion polymerase genes influence treatment outcome in malignant mesothelioma. | GoriΔar K et al. | β | 2014 | β |
| Single-nucleotide polymorphisms in SLC22A23 are associated with ulcerative colitis in a Canadian white cohort. | Serrano LeΓ³n A et al. | β | 2014 | β |
| TGFBR1 tagging SNPs and gastric cancer susceptibility: a two-stage case-control study in Chinese population. | Chen J et al. | β | 2014 | β |
| The association between single nucleotide polymorphisms of GSK 3Ξ² gene and sporadic Alzheimer's disease in a cohort of southern Chinese Han population. | Li J et al. | β | 2014 | β |
| The association of single nucleotide polymorphism of the Fyn gene with sporadic Alzheimer's disease in the Chinese Han population. | Li J et al. | β | 2014 | β |
| The roles of Ca2+/NFAT signaling genes in Kawasaki disease: single- and multiple-risk genetic variants. | Wang W et al. | β | 2014 | β |
| Variants of CEP68 gene are associated with acute urticaria/angioedema induced by multiple non-steroidal anti-inflammatory drugs. | Cornejo-GarcΓa JA et al. | β | 2014 | β |
| ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression. | Magdy T et al. | β | 2013 | β |
| A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. | Urabe Y et al. | β | 2013 | β |
| ALCAM--novel multiple sclerosis locus interfering with HLA-DRB1*1501. | Wagner M et al. | β | 2013 | β |
| Analysis of sex hormone genes reveals gender differences in the genetic etiology of blood pressure salt sensitivity: the GenSalt study. | Kelly TN et al. | β | 2013 | β |
| Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. | Liu H et al. | β | 2013 | β |
| Association between MSX1 SNPs and nonsyndromic cleft lip with or without cleft palate in the Korean population. | Kim NY et al. | β | 2013 | β |
| Association between putative functional variants in the PSMB9 gene and risk of melanoma--re-analysis of published melanoma genome-wide association studies. | Qian J et al. | β | 2013 | β |
| Associations between the risk of tooth agenesis and single-nucleotide polymorphisms of MSX1 and PAX9 genes in nonsyndromic cleft patients. | Seo YJ et al. | β | 2013 | β |
| Candidate gene association studies: a comprehensive guide to useful in silico tools. | Patnala R et al. | β | 2013 | β |
| Chiari malformation type I: a case-control association study of 58 developmental genes. | Urbizu A et al. | β | 2013 | β |
| Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. | Richardson K et al. | β | 2013 | β |
| Genetic polymorphism and prostate cancer aggressiveness: a case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans. | Bensen JT et al. | β | 2013 | β |
| Genetic polymorphisms in RNA binding proteins contribute to breast cancer survival. | Upadhyay R et al. | β | 2013 | β |
| Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors. | Song JY et al. | β | 2013 | β |
| Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau. | Leng S et al. | β | 2013 | β |
| Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. | Hofmann S et al. | β | 2013 | β |
| Genomic variation in the MAP3K5 gene is associated with Ξ²-thalassemia disease severity and hydroxyurea treatment efficacy. | Tafrali C et al. | β | 2013 | β |
| Genotype and age at Parkinson disease diagnosis. | Searles Nielsen S et al. | β | 2013 | β |
| GLiMMPS: robust statistical model for regulatory variation of alternative splicing using RNA-seq data. | Zhao K et al. | β | 2013 | β |
| Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. | Permuth-Wey J et al. | β | 2013 | β |
| Impact of interleukin-10 gene polymorphisms on survival in patients with colorectal cancer. | Ting WC et al. | β | 2013 | β |
| Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning? | Ghoussaini M et al. | β | 2013 | β |
| Interaction between Ξ³-aminobutyric acid A receptor genes: new evidence in migraine susceptibility. | Quintas M et al. | β | 2013 | β |
| No association of SORT1 gene polymorphism with sporadic Alzheimer's disease in the Chinese Han population. | Zeng F et al. | β | 2013 | β |
| Polymorphisms in inflammation pathway genes and endometrial cancer risk. | Delahanty RJ et al. | β | 2013 | β |
| Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients--potential differential effects by radiotherapy? | Seibold P et al. | β | 2013 | β |
| Polymorphisms in the SUFU gene are associated with organ injury protection and sepsis severity in patients with Enterobacteriacea bacteremia. | Henao-MartΓnez AF et al. | β | 2013 | β |
| Potentially functional polymorphisms in ATG10 are associated with risk of breast cancer in a Chinese population. | Qin Z et al. | β | 2013 | β |
| Serum levels of the chemokine CXCL13, genetic variation in CXCL13 and its receptor CXCR5, and HIV-associated non-hodgkin B-cell lymphoma risk. | Hussain SK et al. | β | 2013 | β |
| Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. | Randall JC et al. | β | 2013 | β |
| Systematic identification of trans eQTLs as putative drivers of known disease associations. | Westra HJ et al. | β | 2013 | β |
| The genetic basis for interindividual immune response variation to measles vaccine: new understanding and new vaccine approaches. | Haralambieva IH et al. | β | 2013 | β |
| The relationship between single nucleotide polymorphisms of the NTRK2 gene and sporadic Alzheimer's disease in the Chinese Han population. | Zeng F et al. | β | 2013 | β |
| TNFRSF10B polymorphisms and haplotypes associated with increased risk of death in non-small cell lung cancer. | Schabath MB et al. | β | 2013 | β |
| Variation in the Ξ³-glutamyltransferase 1 gene and risk of chronic pancreatitis. | Brand H et al. | β | 2013 | β |
| A common BACE1 polymorphism is a risk factor for sporadic Creutzfeldt-Jakob disease. | Calero O et al. | β | 2012 | β |
| A functional polymorphism at microRNA-629-binding site in the 3'-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population. | Yang L et al. | β | 2012 | β |
| A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma. | Zhao B et al. | β | 2012 | β |
| A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma. | Osman W et al. | β | 2012 | β |
| A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1. | Urabe Y et al. | β | 2012 | β |
| Antipsychotic-induced movement disorders in long-stay psychiatric patients and 45 tag SNPs in 7 candidate genes: a prospective study. | Bakker PR et al. | β | 2012 | β |
| Association between genetic variants in DNA and histone methylation and telomere length. | Kim S et al. | β | 2012 | β |
| Association between PAX9 single-nucleotide polymorphisms and nonsyndromic cleft lip with or without cleft palate. | Lee JK et al. | β | 2012 | β |
| Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. | Osman W et al. | β | 2012 | β |
| Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies. | Hirata Y et al. | β | 2012 | β |
| Common genetic polymorphisms of microRNA biogenesis pathway genes and breast cancer survival. | Sung H et al. | β | 2012 | β |
| Common genetic variants in the microRNA biogenesis pathway are not associated with breast cancer risk in Asian women. | Sung H et al. | β | 2012 | β |
| Common variants in MAGI2 gene are associated with increased risk for cognitive impairment in schizophrenic patients. | Koide T et al. | β | 2012 | β |
| DNA repair polymorphisms and treatment outcomes of patients with malignant mesothelioma treated with gemcitabine-platinum combination chemotherapy. | ErΔulj N et al. | β | 2012 | β |
| DNA repair polymorphisms influence the risk of second neoplasm after treatment of childhood acute lymphoblastic leukemia. | ErΔulj N et al. | β | 2012 | β |
| Functional differences exist between TNFΞ± promoters encoding the common -237G SNP and the rarer HLA-B*5701-linked A variant. | Simpson PD et al. | β | 2012 | β |
| Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer. | Zhou F et al. | β | 2012 | β |
| Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. | Leng S et al. | β | 2012 | β |
| Genetic polymorphisms of the transcription factor NFATc4 and development of new-onset diabetes after transplantation in Hispanic kidney transplant recipients. | Chen Y et al. | β | 2012 | β |
| Genetic variations in key microRNA processing genes and risk of head and neck cancer: a case-control study in Chinese population. | Ma H et al. | β | 2012 | β |
| Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh. | Pierce BL et al. | β | 2012 | β |
| Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. | Du R et al. | β | 2012 | β |
| Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease. | Chen X et al. | β | 2012 | β |
| HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. | Ward LD et al. | β | 2012 | β |
| Linking disease associations with regulatory information in the human genome. | Schaub MA et al. | β | 2012 | β |
| Meta-analysis identifies common variants associated with body mass index in east Asians. | Wen W et al. | β | 2012 | β |
| NMDA receptor genotypes associated with the vulnerability to develop dyskinesia. | Ivanova SA et al. | β | 2012 | β |
| Physiology and Endocrinology Symposium: How single nucleotide polymorphism chips will advance our knowledge of factors controlling puberty and aid in selecting replacement beef females. | Snelling WM et al. | β | 2012 | β |
| Polymorphisms in oxidative stress genes, physical activity, and breast cancer risk. | McCullough LE et al. | β | 2012 | β |
| Possible genetic predisposition to lymphedema after breast cancer. | Newman B et al. | β | 2012 | β |
| Putatively functional PLCE1 variants and susceptibility to esophageal squamous cell carcinoma (ESCC): a case-control study in eastern Chinese populations. | Hu H et al. | β | 2012 | β |
| Resequencing of the auxiliary GABA(B) receptor subunit gene KCTD12 in chronic tinnitus. | Sand PG et al. | β | 2012 | β |
| Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers. | Flores KG et al. | β | 2012 | β |
| SNP variants within the vanilloid TRPV1 and TRPV3 receptor genes are associated with migraine in the Spanish population. | CarreΓ±o O et al. | β | 2012 | β |
| Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity. | Kim S et al. | β | 2012 | β |
| TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications. | Yin J et al. | β | 2012 | β |
| The influence of gemcitabine pathway polymorphisms on treatment outcome in patients with malignant mesothelioma. | ErΔulj N et al. | β | 2012 | β |
| The regulatory effect of miRNAs is a heritable genetic trait in humans. | Geeleher P et al. | β | 2012 | β |
| The role of the kallikrein-kinin system genes in the salt sensitivity of blood pressure: the GenSalt Study. | Gu D et al. | β | 2012 | β |
| A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. | Richardson K et al. | β | 2011 | β |
| Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. | Ma H et al. | β | 2011 | β |
| Association of a novel functional promoter variant (rs2075533 C>T) in the apoptosis gene TNFSF8 with risk of lung cancer--a finding from Texas lung cancer genome-wide association study. | Wei S et al. | β | 2011 | β |
| Common genetic polymorphisms of microRNA biogenesis pathway genes and risk of breast cancer: a case-control study in Korea. | Sung H et al. | β | 2011 | β |
| Data integration workflow for search of disease driving genes and genetic variants. | Karinen S et al. | β | 2011 | β |
| Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children. | Huen K et al. | β | 2011 | β |
| Exploration of relationships between production and fertility traits in dairy cattle via association studies of SNPs within candidate genes derived by expression profiling. | Pimentel EC et al. | β | 2011 | β |
| Genome-wide approaches in the study of microRNA biology. | Wilbert ML et al. | β | 2011 | β |
| Genome-wide association analysis of soluble ICAM-1 concentration reveals novel associations at the NFKBIK, PNPLA3, RELA, and SH2B3 loci. | ParΓ© G et al. | β | 2011 | β |
| Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophages. | Bol SM et al. | β | 2011 | β |
| GWAS SNP Replication among African American and European American men in the North Carolina-Louisiana prostate cancer project (PCaP). | Xu Z et al. | β | 2011 | β |
| ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework. | Zhang K et al. | β | 2011 | β |
| Identifying functional single nucleotide polymorphisms in the human CArGome. | Benson CC et al. | β | 2011 | β |
| Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk. | Permuth-Wey J et al. | β | 2011 | β |
| LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer. | Permuth-Wey J et al. | β | 2011 | β |
| MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium. | Permuth-Wey J et al. | β | 2011 | β |
| Mitochondrial DNA copy number is modulated by genetic variation in the signal transducer and activator of transcription 3 (STAT3). | Gianotti TF et al. | β | 2011 | β |
| Nominal association between a polymorphism in DGKH and bipolar disorder detected in a meta-analysis of East Asian case-control samples. | Takata A et al. | β | 2011 | β |
| Partial-genome evaluation of postweaning feed intake and efficiency of crossbred beef cattle. | Snelling WM et al. | β | 2011 | β |
| Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages. | Bol SM et al. | β | 2011 | β |
| TNFRSF1B +676 T>G polymorphism predicts survival of non-small cell lung cancer patients treated with chemoradiotherapy. | Guan X et al. | β | 2011 | β |
| Algorithms aim to improve hunt for disease markers. | Torres C | β | 2010 | β |
| Are adolescents with ADHD interested in genetic testing for nicotine addiction susceptibility? | Herbert LJ et al. | β | 2010 | β |
| Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer. | Schildkraut JM et al. | β | 2010 | β |
| Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. | Peloso GM et al. | β | 2010 | β |
| Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. | Chinn LW et al. | β | 2010 | β |
| Genome-wide association studies: a primer. | Corvin A et al. | β | 2010 | β |
| MicroRNA binding site polymorphisms as biomarkers of cancer risk. | Pelletier C et al. | β | 2010 | β |
| Shrunken methodology to genome-wide SNPs selection and construction of SNPs networks. | Liu Y et al. | β | 2010 | β |
| SPOT: a web-based tool for using biological databases to prioritize SNPs after a genome-wide association study. | Saccone SF et al. | β | 2010 | β |
| The genetic architecture of lipoprotein subclasses in Gullah-speaking African American families enriched for type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR). | Divers J et al. | β | 2010 | β |
| Genomics software: The view from 10,000 feet. | Weale ME | β | 2009 | β |