BAI3, a seven transmembrane domain cell adhesion molecule, as well as PTPRM, a single transmembrane receptor tyrosine kinase that mediates homophilic cell recognition and is supported at a more modest level of statistical confidence, are both expressed in vasculature [183, 184]. Identifying these genes fits with the idea that control and regulation of angiogenesis and vascular functions plays important roles in determining the richness of cerebral cortex and other areas of adult brains [184] in ways that have consequences for a variety of interesting brain based phenotypes. In addition, there is substantial neuronal expression of PTPRM in cortical and cerebellar cortical neurons [172, 183].
