Samples: In fatSNP1, the resultant set of SNPs (excluding those for which data were already available from the GWAS study) were genotyped in a subset of the GWAS samples from the earlier study(4). This fatSNP1 sample comprised 479 UK cases with schizophrenia and the 1958 birth cohort control sample (N=1445) used by the Welcome Trust Case Control Consortium(15) that we had also used in our GWAS study. The results of fatSNP1 were used to select SNPs for follow up in additional samples using criteria detailed below.