perceptive, and cognitive functions related to AUD [73]. For example, AUD-related alterations in callosal fibers are associated with changes in executive function [45] and decision-making deficits [60]. In particular, reduced integrity of the genu of the corpus callosum could be associated with poorer working memory performance [74]. However, another study could not find a direct correlation between the integrity of the callosal fibers and cognitive performance in AUD, but a correlation between the integrity of the cingulum, executive functions, and psychomotor performance [54]. Furthermore, the cingulum bundle, as well as the fornix form two major fiber tracts of the limbic system, and their degradation, might promote deficits in emotion regulation processes [75]. For example, lower FA in frontoparietal and corticolimbic networks as well as in deep WM structures, like the internal capsule, has been linked to higher alcohol cue reactivity in heavy drinkers [76]. In addition, lower visuospatial memory performance, another neurobehavioral consequences of heavy chronic alcohol consumption (e.g., [77] for review), has been associated with reduced commissural FA in AUD patients compared to controls [44]. Furthermore, the corpus callosum and the cingulum have been found to interconnect key nodes of large-scale brain networks, such as the default mode network,
