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Chunk #95 — Summary and Future Directions

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Advances in Electrophysiological Research.
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Future research will focus on newer and more effective electrophysiological techniques available for neurocognitive, genetic, and clinical research. Given that electrophysiological measures hold promise as effective endophenotypes for gene discovery, these tools have potential for drug discovery as well as for a range of clinical applications. A variety of sophisticated statistical techniques (e.g., developmental trajectories), which will allow systematic research on several key electrophysiological measures, will be useful to highlight longitudinal aspects of cognitive development as well as the nature and course of the disorder under investigation. Furthermore, recent research has capitalized on the potential of using complementary information from neuroimaging methods and electrophysiological measures by performing multimodal brain imaging (Uludag and Roebroeck 2014) (e.g., combined EEG–fMRI studies), which has offered and will offer remarkable findings to understand the disorder in a better light than any single method can potentially promise (He and Liu 2008). The studies using multimodal imaging approaches are growing rapidly by implementing a simultaneous EEG–fMRI protocol aimed at achieving both high temporal and spatial resolution of human brain function (Huster et al. 2012; Mantini et al.