promise (He and Liu 2008). The studies using multimodal imaging approaches are growing rapidly by implementing a simultaneous EEG–fMRI protocol aimed at achieving both high temporal and spatial resolution of human brain function (Huster et al. 2012; Mantini et al. 2010), and this approach already has been found to be highly useful in many clinical conditions (Gotman and Pittau 2011; Shafi et al. 2012), including alcoholism (De Ridder et al. 2011; Karch et al. 2008). As a final note, as advancement in technology enhances the opportunity for further applications in clinical research in all spheres, many more tools are being developed in the electrophysiological arsenal to be effectively used to address the current and future challenges.
