). Meta-analysis showed that these gene effects became less significant when combined AAs and EAs, but became a little more significant when combined EAs and Australians (data not shown). In spite of this, all risk alleles (OR>1; Table 1 ) of these 29 SNPs (except for rs1744134, rs1482451 and rs3003672) were the minor alleles (f<0.5) in both AAs and EAs (Table S4). Additionally, sex, age and admixture effects did not significantly affect our results (data not shown).
