The Australian twin-family study of alcohol use disorder (OZALC study) derives from telephone diagnostic interview studies of two general population volunteer cohorts of Australian twins (cohort 1, mostly born 1940–1964; cohort 2, born 1964–71) and the spouses of the former cohort – a total of over 11,000 families. The data used in the present study is from the publicly available data from the Genome wide Association Study of Alcohol Use and Alcohol Use Disorder in Australian Twin-Families (OZALC GWAS) – Study Accession: phs000181.v1.p1. The details about these subjects were described elsewhere (Grant et al., 2009; Lind et al., 2010). Genotyping data using the ILLUMINA HumanCNV370v1 (total 343,955 SNPs) are available for 4,119 individuals in this data set. After merging with pedigree and phenotypes, we removed one from each of 44 MZ twins and 72 outliers based on the data description, and 669 individuals with unknown case status. Consequently, there were 3137 individuals with MaxDrinks left for further analysis (1708 males and 1429 females).
