Several browser tracks are updated on a regular basis. The RefSeq and mRNA tracks, which show sequences from all organisms in GenBank aligned to all of the Genome Browser assemblies, are updated nightly. The RefSeq tracks now include alignments of non-coding genes. EST tracks are updated with new data deposited in GenBank on a weekly basis. Other tracks that are updated each night include the Mammalian Gene Collection (MGC) tracks (18) on the human, mouse, rat, cow and frog browsers, the Consensus Coding Sequence (CCDS) tracks (19) on the human and mouse, and the ORFeome Clones tracks (which show alignments of clones from the ORFeome Collaboration) on the human genome. The Ensembl Genes (6) track, available on ∼25 different organisms, and the Database of Genomic Variants (DGV) track (20,21), which contains genomic variations observed in healthy human individuals, are updated whenever a new version is released.