ConsensusPathDB is a database that integrates interaction data from heterogeneous resources for human functional interactions in order to create a more complete and less biased picture of the cellular interactions. It can be used in many ways—for example, to retrieve network topologies necessary for mathematical simulations, to interpret gene lists, to assess the distribution of interaction knowledge across interaction databases, or to carry out topological analysis with the integrated human interaction network, which, according to our analysis, provides quite different results compared to topological analysis of the separate interaction databases (results will be published elsewhere).