Apart from the possibility to export interaction networks from the visualization environment, the user can upload an interaction network file in any of three different formats: BioPAX (level 2), PSI-MI (level 2.5) and SBML (level 2) (27). If the physical entities from the uploaded file are annotated with external identifiers, these entities and their interactions are mapped to the interaction network in the database and matching information is indicated. Thereby, the model can be validated against existing interaction knowledge stored in the database, and extended in the context of the database content.
