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Chunk #4 — Methods and Materials — Neuroimaging Methods — fMRI Processing

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General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance.
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Initial preprocessing steps, implemented in Automated Image Registration software (http://bishopw.loni.ucla.edu/AIR), were slice-time and motion correction, and removal of linear trends and significant time series outliers. The images were then spatially normalized using a nonlinear algorithm and spatially smoothed (8-mm full-width at half-maximum Gaussian kernel) using SPM5 (http://www.fil.ion.ucl.ac.uk/spm/software).