Demographics of the COGA samples are summarized in Table 1. There were 3,451 cases who met criteria for DSM-IV alcohol dependence or DSM-5 AUD, and 1,616 alcohol-exposed controls (after exclusions for age and other drug dependence diagnoses); 7,203 participants had data on DSM-5 AUD diagnostic criterion count. Given the ascertainment criteria for the COGA sample, more than half of the participants (N=4,842) had a positive family history of AUD (FH+) with more than half of those being AUD cases (N=2,531).
