There is a paucity of data examining possible P3b reductions in treatment-naïve AUD adolescents without substance or psychiatric comorbidity. Published studies on adolescents with AUDs (e.g., Bauer and Hesselbrock, 2003; Carlson et al., 1999) focus on treated samples with childhood externalizing diagnoses and substance (other than alcohol) involvement. Studies of treatment-naïve adolescent AUD samples who are free of psychiatric and other substance comorbidity will help tease out the contribution of alcohol exposure to the P3b reduction because adolescents have much less such exposure than do older individuals who have been drinking for much longer.
