For our psychiatric and behavior-related phenotypes, we ultimately retained GWAS summary data reflecting studies of Alzheimer’s disease (Lambert et al. 2013), angry temperament (Mick et al. 2014), anorexia nervosa (L. Duncan et al. 2017), attention deficit-hyperactivity disorder (ADHD; Demontis et al. 2017), autism (Anney et al. 2017), bipolar disorder (BD; Sklar et al. 2011; Hou et al. 2016), cigarette smoking (ever-smoked status; The Tobacco and Genetics Consortium 2010), major depressive disorder (Ripke et al. 2013), trait neuroticism (Turley et al. 2018), obsessive-compulsive disorder (OCD; Arnold et al. 2017), Parkinson’s disease (Pickrell et al. 2016), schizophrenia (SZ; Ripke et al. 2014), and Tourette Syndrome (personal communication from PGC Working Group). Collectively, these phenotypes were treated as a set. For phenotypes that are known or suspected to involve alterations to immune cells and/or inflammatory signaling, we ultimately retained GWAS data reflecting allergy (any, self-reported; Hinds et al. 2013; Pickrell et al. 2016), asthma (self-reported; Pickrell et al. 2016), atopic dermatitis (EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium 2015), childhood ear infection (self-reported; Pickrell et al. 2016), celiac disease (Dubois et al.
