Chunk #30 — RESULTS — Gene Expression Profiling of hESCs, iPSCs, and Cells Differentiated from Them

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Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions.

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A closer analysis of the pluripotency network is shown in Table 2. As expected, many pluripotency genes including Oct4, Nanog, and Sox2 were highly expressed in iPSCs and hESCs. Of the genes shown, little difference was seen between the two iPSC lines and hESC line H9. The differences observed were similar in magnitude to those seen in comparisons among different hESC lines and the same line grown in different laboratories [18].