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Chunk #3 — Materials and methods — Subjects

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COMT Val158Met modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers.
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We recruited 124 non-treatment-seeking cigarette smokers in and around New Haven, Connecticut through newspaper advertisements and flyers. All participants were between 18 and 50 years old and smoked between 10 and 25 cigarettes per day during the past year. The study sample included 100 smokers that were described in a previous study (23) as well as 24 additional smokers. The demographics are shown in Table 1.