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Chunk #41 — 2. Methods and Materials — 2.4. Statistical Methodology — 2.4.2. Age variation of genotypic effects — Relation of genotypic values to phenotypic correlations

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Genetic correlates of the development of theta event related oscillations in adolescents and young adults.
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Given that the phenotypic variables show high degrees of correlation, as shown in Figure 2 and described in section 3.1.2, it would be expected that regression models of correlated phenotypic variables using the same model structure and using the same independent variables would exhibit corresponding values for the parameter estimates, including the estimates for the effects of genotype. On the other hand, it also would be expected that some SNPs would be associated with biological factors acting in a spatially localized manner, while others would be associated with factors acting more globally. Because of the small number of SNPs available, a direct test of the similarity of phenotypic intramodal and intermodal correlations and the correspondences of association trajectories between different scalp locations (intramodal) and different modalities (intermodal) across SNPs was not possible.