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Chunk #40 — 2. Methods and Materials — 2.4. Statistical Methodology — 2.4.2. Age variation of genotypic effects — Identification of Significant SNPs

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Genetic correlates of the development of theta event related oscillations in adolescents and young adults.
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the regression calculations were performed, in the interest of condensation of information and ease of interpretation results are also provided for 7 overlapping 3 year age ranges extending from age 12 to 24. (Ranges: 12–15, 13.5–16.5, 15–18, 16.5–19.5, 18–21, 19.5–22.5, 21–24.) Medians of p-values across the age-ranges were calculated to provide coarse-grained results. The concentration of measure of the range of p-values introduced by use of the median was considerable, particularly in the range 0 < p < 10−2 and introduced a corresponding bias in the direct application of the Storey-Tibshirani algorithm. As a consequence, the false discovery proportion threshold derived from the calculation on the raw p-values was used to determine the appropriate threshold for the control of the false discovery rate in the median p-values.