to a region on mouse chromosome 9 where multiple studies have found QTLs for alcohol preference (Phillips et al., 1994, 1998; Tarantino et al., 1998). It is of interest in both of these cases that while the QTLs were found to be syntenic that the exact phenotypes between humans and mice did not necessarily overlap. These findings suggest that trying to match exact phenotypes in humans and animals may not be necessary or even optimal for determining whether similar genes influence alcohol-related behaviors between the two species. While these two examples offer additional support for these QTLs and are promising for narrowing these QTLs, specific QTGs have not yet been confirmed for these phenotypes.
