Chunk #37 — The search for gene variants related to alcohol sensitivity (See Table 1) — Additional genes of potential interest

Source

A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity.

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Zinc-finger gene ZNF699 (chromosome 19p13.2) is related to Drosophila gene “hang”, which is associated with increased alcohol tolerance (Scholz et al., 2005) and to QTLs involved in alcohol sedation in mice (e.g., Bennett and Johnson, 1998; Ehringer et al., 2002; Markel et al., 1997; Riley et al., 2006). In humans, several gene variants (e.g., rs7254880) might relate to alcohol dependence (Riley et al., 2006).