Similar to the original cohort (Table 2), alcohol significantly impaired smooth pursuit gain (p < 0.0001), pro-saccade latency (p < 0.0001) and velocity (p < 0.0001), and anti-saccade latency in the second cohort (p < 0.0001). Impairment was most evident at peak BrAC (60 min) for these measures. While alcohol did marginally affect anti-saccade accuracy in the second cohort (p = 0.013), this effect did not reach the significance threshold after correction for multiple testing and was therefore not considered replicated. In contrast to results observed in the original cohort, alcohol did not significantly decrease pro-saccade accuracy in the second cohort. Anti-saccade velocity was not significantly affected by alcohol in either cohort, though there was a trend in the original cohort (p = 0.009). The second set of analyses directly comparing both cohorts revealed no differences of the seven eye tracking variables (Table 2 and Figure 2a - c). These results provide evidence for a full replication of the majority of the eye movement findings reported in Roche and King (2010).
