Univariate and cross-trait LD score regression intercepts, estimates of SNP-based heritability, genetic covariances, and genetic correlations for the LD score regression analysis with COGA removed are presented in Table S8. Manhattan plots and quantile-quantile plots depicting SNP effects on the residual components of the model are included in Figures S4 - S11. Descriptive statistics for phenotypic measures in the COGA analytic sample can be found in Table S2. Briefly here, the sample sizes in COGA for PGS analyses were n=1,118 in adolescence, n=2,762 in early adulthood, and n=5,255 in adulthood. Average drinking days per year in COGA were M=36.15 (SE=1.60) in adolescence, M=96.45 (SE=1.75) in early adulthood, and M=98.41 (SE=1.67) in adulthood.
