We also identified positive genetic associations between POU and other behavioral and psychiatric traits, such as mood swings (rg = 0.40, p = 1.04E−13), risk-taking behavior (rg = 0.38, p = 2.09E−08), major depressive disorder (rg = 0.44, p = 1.59E−10), insomnia (rg = 0.39, p = 6.88E−11), loneliness (rg = 0.28, p = 4.81E−06), and irritability (rg = 0.27, p = 1.74E−05).
