After adjusting for the first-degree family history, PRS were still significant (AUD: Beta=2.70, SE=0.44, P-value=6.83E-10; AUD diagnosis criterion count: Beta=1.04, SE=0.13, P-value=1.55E-15). The interactions between PRS and the first-degree family history were not significant for either AUD or AUD diagnosis criterion count (P-values=0.60 and 0.22, respectively).
