Chunk #21 — Do cannabinoids cause short-lived positive psychotic symptoms, negative symptoms and cognitive deficits in the general population? — Cognitive deficits
In summary, both natural and synthetic cannabinoids administered via different routes can produce a range of transient, dose-related, schizophrenia-like positive, negative and cognitive symptoms in individuals without any obvious risk of schizophrenia. Some but not all individuals experience robust psychotomimetic effects. What makes some individuals more vulnerable than others to the psychotomimetic effects of cannabinoids is not clear. In addition to the effects described above, cannabinoids produce a plethora of other acute transient effects, including euphoria, relaxation, increased appetite, anxiolysis or anxiety, tachycardia, the intensification of mundane sensory experiences [3, 98, 105].
