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Chunk #81 — Results and discussion — NIA-AA biomarker analysis in specific brain regions of 3xTg-AD mice (1-month post alcohol) — Additional brain regions

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Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.
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No changes in Aβ42/40 ratio or total Tau protein were detected in samples from nucleus accumbens (Acb), medial hippocampus (MHPC), lateral hippocampus (LHPC), CA1 subregion of the hippocampus (CA1), and the medial entorhinal cortex (MEC; data not shown).