Chunk #33 — Results — A single effective sample size does not capture all variance inflations in genotype frequency estimations, but it provides a good approximation
Figure 2 shows αG,sibpair’s of the three genotypes as a function of p; also shown are the genotype frequency variance (multiplied by the sample size). Variances of genotype frequencies calculated from independent samples are shown in solid lines as a comparison. It can be seen from Figure 2 that the variance inflation of allele frequency is distinct from those of genotype frequencies in that its α is a constant value 2/3 independent of p. It illustrates that one should not expect a single parameter to correct the variance inflation in correlated samples for all circumstances.
