Chunk #18 — 3. Results — 3.3. Evaluating the interaction between the 5-HTTLPR short allele and childhood maltreatment in predicting cross-sectional snapshots of adult depression

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Serotonin transporter gene moderates childhood maltreatment's effects on persistent but not single-episode depression: replications and implications for resolving inconsistent results.

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In Dunedin, between 15.6% and 17.1% of individuals were diagnosed with past-year major depression at any given cross-section. In E-risk, between 11.0% and 13.6% of individuals were diagnosed with past-year major depression at any given cross-section. Fig. 2 shows the association between childhood maltreatment and adult depression at each of the 4 assessment periods in adulthood by 5-HTTLPR genotype in Dunedin (Panel A) and E-risk (Panel B).