stages of maturation. Their capacitance was larger than that of both the other groups (with a significant results compared with controls). LR neurons were hyperexcitable and were characterized by a narrower, higher amplitude spike and a higher amplitude fast AHP at all stages of maturation. The resemblance in the spike shape of the LR to that of fast spiking interneurons suggests immediately that they too will have properties of fast spiking abilities. The NR neurons, on the other hand, have the large fast AHP feature but also have reduced sodium currents. These differences hint at what may be a more complicated phenotype of hyperexcitability, with a possible change to hypoexcitability because of changes in the cell or its environment, or by the natural diversity throughout a population.
