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Chunk #23 — Results — Sensitivity Analyses

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The Impact of Polygenic Risk, Parental Separation, and Parental Relationship Discord on Heavy Episodic Drinking Across Adolescence and Young Adulthood in a High-Risk Sample.
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In the EA sample, the patterns of associations from these sensitivity analyses were largely consistent with results from analyses using PGSPAU. Parental history of AUD was associated with a more rapid escalation of HED and lower quadratic growth of HED. Both parental separation and parental relationship discord were associated with higher intercepts. In the AA sample, the patterns of associations from these sensitivity analyses were virtually identical with results from analyses using PGSPAU. Parental history of AUD was not associated with the intercept and the longitudinal course of HED. However, in the model that included parental history instead of PGSPAU, parental relationship discord was associated with more rapid escalation of HED and lower quadratic growth.