Reflecting these data, LR has been compared across higher and lower AUD risk groups (e.g., children of alcoholics vs. FH negative subjects) while controlling for age, the number of years of drinking, percent body water, and the prior pattern of the use of alcohol and other drugs (Schuckit & Gold, 1988; Schuckit & Smith, 2000). However, while alcohol outcomes associated with a low LR have been documented in recent longitudinal evaluations (Trim et al., 2008), the associations between LR and the development of AUDs over time has not yet been fully examined. Also, potential interactions among predictors of AUDs in the context of a low LR have rarely been evaluated.
