allele at rs9298626 and the minor allele at rs1451240 has a frequency of 18% but was not associated with DSM-5 cocaine use disorder (p = 0.14). Because the frequencies and odds ratio of the haplotype with both minor alleles is nearly identical to that of the single SNP analysis for rs9298626 and the fact that the other haplotype containing the minor allele of rs1451240 is not associated with DSM-5 cocaine use disorder, we conclude that the functional allele responsible for this association is in high LD with the low frequency variant, rs9298626.
